Thursday, April 22, 2010

Gilead stops hepatitis drug test after ‘adverse events’

Gilead stops hepatitis drug test after ‘adverse events’
Tuesday, April 20, 2010

Citing “significant laboratory abnormalities and adverse events” in patients, Gilead Sciences stopped a clinical test of a hepatitis C drug.

The Foster City company (NASDAQ: GILD) will review data from this Phase II test of GS 9450, a caspase inhibitor. The company has been studying it for treatment of hepatitis C and also for nonalcoholic steatohepatitis.

Gilead licensed the drug from LG Life Sciences Inc. in 2007, paying $20 million upfront for the rights to the drug except in Korea, China and India. The company also agreed to pay for a collaborative research program and to pay milestones of up to $182 million if the drug did well in development.

“Patient safety is Gilead’s top priority,” the business said in a press release.

Gilead didn’t describe the problems in detail.

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